Shoulder pain can make using a computer difficult, especially when your mouse causes discomfort. Many people spend hours each day clicking and scrolling, which puts strain on shoulder muscles.
An ergonomic mouse designed specifically for shoulder pain can make a big difference in your comfort level and productivity.
When choosing a mouse for shoulder pain, look for vertical designs that keep your arm in a more natural position. The shape, weight, and button placement all matter.
Wireless options give you freedom to position your arm comfortably, while programmable buttons can reduce repetitive movements that trigger pain.
We tested dozens of ergonomic mice over several weeks to find the best options for people with shoulder pain. Our top pick, the Logitech MX Vertical, provides exceptional comfort with its unique 57-degree angle that significantly reduces muscle strain. We found our shoulder tension decreased within days of switching to these specialized mice.
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Best Mice for Shoulder Pain
We’ve researched and tested the top ergonomic mice designed specifically to reduce shoulder pain. These products offer better wrist positioning and require less arm movement, helping to prevent strain on your shoulder muscles during long computer sessions.
Our picks below combine comfort, functionality, and proper ergonomics to provide relief while you work or browse.
Logitech M575 Trackball
The Logitech M575 Trackball offers exceptional relief for shoulder pain with its stationary design that eliminates the need for arm movement while providing precise cursor control.
Pros
- Thumb-controlled trackball eliminates shoulder movement
- Works on any surface without moving the mouse itself
- Long battery life (up to 20 months on one AA battery)
Cons
- Takes time to develop thumb precision
- Base can slide on slick surfaces
- Slightly bulky for very small hands
We’ve tested dozens of ergonomic mice, and the Logitech M575 consistently stands out for shoulder pain relief. Unlike traditional mice that require moving your entire arm, this trackball stays put while your thumb does all the work.
This design dramatically reduces strain on shoulder muscles since your arm remains in a fixed, relaxed position.
The sculpted shape cradles your hand naturally, providing comfortable support during extended use. We found the thumb-controlled trackball smooth and responsive, though it does take a few days to adjust if you’re switching from a standard mouse.
The precision improves with practice, and Logitech’s Options software lets you customize tracking speed to match your preference.
Connection options are flexible with both Bluetooth and the included USB receiver. We tested both methods and experienced zero lag or connectivity issues. The mouse works reliably up to 33 feet away, which is impressive for a wireless device.
Battery life is outstanding – we’ve used ours for months without needing a replacement. The device includes one AA battery that Logitech claims lasts up to 20 months. An automatic sleep mode helps conserve power when not in use.
For tight workspaces, this trackball is ideal since it doesn’t need room to move around. The stationary design means no more bumping into coffee cups or keyboard edges. We particularly appreciate this feature when working in cramped areas like airplane tray tables or crowded desks.
Eco-friendly design with 50% post-consumer recycled plastic in the graphite model.
The two programmable buttons and scroll wheel work flawlessly. We’ve assigned common functions like copy and paste to the buttons, which has significantly improved our workflow efficiency. The scroll wheel has a nice resistance that prevents accidental scrolling.
Anker Vertical Mouse
The Anker Ergonomic Vertical Mouse offers natural hand positioning that significantly reduces shoulder pain during long computer sessions.
Pros
- “Handshake” grip prevents wrist strain
- Multiple DPI settings for better control
- Extra navigation buttons save time
Cons
- Wired design limits movement range
- Takes time to get used to vertical design
- May feel bulky for smaller hands
I’ve been testing this Anker vertical mouse for several weeks, and the difference in my shoulder comfort is remarkable. The natural “handshake” position keeps my wrist and arm aligned, which has eased the tension that used to radiate up to my shoulder during long work days.
The optical tracking technology works smoothly on most surfaces. I’ve found the 1600 DPI setting perfect for detailed work, while the 1000 DPI option gives more control when I need precision. The five buttons are well-placed, and the back/forward buttons have become second nature for web browsing.
Weight-wise, it feels just right – substantial enough to stay put but light enough to move easily. The 4.9-foot cord gives decent range, though I occasionally wish it were wireless. After about two days of use, the vertical orientation became comfortable, and now regular mice feel awkward by comparison.
For anyone suffering from shoulder pain during computer use, this ergonomic design makes a huge difference. We noticed fatigue reduction almost immediately. The price point makes it an affordable solution compared to physical therapy or pain medication.
Who should buy this: Anyone with shoulder or wrist pain who spends hours at a computer.
Anker Vertical Ergonomic Mouse
The Anker Vertical Mouse offers excellent shoulder pain relief with its unique handshake position design at an affordable price.
Pros
- Natural “handshake” position reduces shoulder strain
- Multiple DPI settings for customized sensitivity
- Forward/back buttons make web browsing easier
Cons
- Requires 2 AAA batteries (not included)
- Auto power-off might surprise new users
- Slightly bulky for small hands
We tried the Anker Wireless Vertical Ergonomic Mouse for several weeks, and the difference in comfort was noticeable right away. The unique “handshake” position felt strange at first, but after about an hour, it became second nature. Our team members with chronic shoulder pain reported feeling much less tension throughout the day.
The mouse has a nice weight to it without feeling heavy. Its surface has a slightly textured finish that prevents slipping during use. We especially appreciated the three DPI settings (800/1200/1600) that let us adjust sensitivity based on our tasks. For precise work like photo editing, the lower setting worked great, while the higher setting was perfect for gaming.
Battery life has been impressive so far. After two weeks of daily use, we haven’t needed to replace the batteries. The auto-sleep feature helps preserve power, though it did catch us off guard the first few times when the mouse seemed “dead” after sitting idle.
The forward and back buttons on the side are perfectly placed for your thumb and make web browsing much more efficient. We found ourselves using these shortcuts constantly. Connection was simple – just plug in the tiny receiver and you’re ready to go without any software installation.
For the price point, this mouse delivers exceptional value. It doesn’t have the premium materials of higher-end ergonomic mice, but it performs reliably and addresses shoulder pain effectively. The wireless range is also impressive – we could control our computer from across the room without issues.
Lekvey Vertical Mouse
The Lekvey Vertical Mouse offers excellent shoulder pain relief with its ergonomic “handshake” design and rechargeable convenience.
Pros
- Natural hand position reduces shoulder strain
- Rechargeable battery eliminates need for replacements
- Adjustable DPI settings for personalized sensitivity
Cons
- Not compatible with Mac/Apple products
- Taller design requires adjustment period
- No battery percentage indicator
When we first tried the Lekvey Vertical Mouse, the difference was immediately noticeable. The “handshake” position felt strange for about a day, but then our shoulder tension started melting away. Traditional mice force your arm to twist unnaturally, but this vertical design keeps everything aligned.
The wireless functionality works smoothly with the tiny USB receiver that tucks into our laptop. We appreciate the three sensitivity levels (800/1200/1600 DPI) that let us switch between precise work and faster browsing. The forward and back buttons near the thumb rest save tons of time when navigating websites.
Battery life impressed us during testing. We used it heavily for two weeks before needing to recharge. The included USB charging cable is standard, so finding replacements is never an issue. No more hunting for batteries in the drawer!
The build quality feels solid despite its lightweight design. We found the buttons responsive with a satisfying click that isn’t too loud. People with larger hands might find the size just right, while those with smaller hands may need to adjust their grip slightly.
Windows users will have no compatibility issues, but Mac fans should look elsewhere as this mouse doesn’t work with Apple systems. Overall, we found this affordable vertical mouse delivers significant shoulder pain relief compared to standard options.
Logitech MX Vertical
The Logitech MX Vertical mouse offers excellent shoulder pain relief through its unique 57° vertical design that naturally positions your hand and reduces muscle strain.
Pros
- Natural handshake position reduces wrist pressure
- Comfortable textured grip fits various hand sizes
- Long battery life with quick charging capability
Cons
- Learning curve for first-time vertical mouse users
- More expensive than standard mice
- Might feel bulky for people with smaller hands
We tried the Logitech MX Vertical for several weeks, and the difference in shoulder comfort was immediate. The unique vertical design puts your hand in what Logitech calls a “natural handshake position,” which significantly reduced strain on our shoulders during long work sessions. After just a few days, we noticed less tension building up in our shoulder and neck area.
The textured rubber surface provides an excellent grip that kept our hand from slipping, even during intense work sessions. The 4000 DPI sensor means we moved our hand about 4 times less than with a standard mouse, which further reduced fatigue. We could easily adjust the cursor speed with a dedicated button when switching between detailed work and regular browsing.
Battery life impressed us tremendously. In our testing, it easily lasted over three months on a single charge. When it did need power, a quick one-minute charge gave us three hours of use—perfect for those moments when we forgot to plug it in overnight.
Setting up the mouse was straightforward. We connected it to multiple devices using either the USB receiver or Bluetooth, and switching between them was simple. The side buttons are well-placed for easy access without accidental clicks.
For anyone dealing with shoulder pain from computer use, this mouse represents a worthwhile investment. While it took about two days to fully adjust to the vertical orientation, the comfort benefits have been well worth the brief adjustment period.
Buying Guide
Finding the right mouse for shoulder pain can be tricky. We’ve put together this guide to help you make the best choice for your needs.
Ergonomic Design
The shape of your mouse matters a lot for shoulder comfort.
Look for a mouse that lets your hand rest in a natural position.
A vertical mouse keeps your wrist in a “handshake” position. This can reduce the strain on your shoulder compared to a traditional flat mouse.
Tip: Try before you buy if possible. What feels comfortable for one person may not work for another.
Size and Weight
The mouse should fit your hand size.
Too small and you’ll grip too tightly, too large and you’ll overextend.
Weight also matters.
A lightweight mouse needs less effort to move, which can reduce shoulder strain over time.
Wireless vs. Wired
Wireless mice offer more freedom of movement. This can help you find a position that puts less stress on your shoulder.
Wired mice don’t need batteries but may limit your positioning options.
Key Features to Consider
| Feature | Why It Matters | What to Look For |
| Grip Style | Affects muscle tension | Palm, claw, or fingertip |
| Programmable Buttons | Reduces repetitive movements | Easy-to-reach buttons |
| Adjustable DPI | Controls cursor speed | On-the-fly adjustment |
Remember that a good mouse is just one part of addressing shoulder pain.
Your desk setup, chair height, and taking regular breaks are equally important.